Absence of deleterious palladin mutations in patients with familial pancreatic cancer.
نویسندگان
چکیده
It has been reported that germline mutations in the palladin gene (PALLD) cause the familial aggregation of pancreatic cancer, but the evidence is weak and controversial. We sequenced the coding regions of PALLD in 48 individuals with familial pancreatic cancer. We did not find any deleterious mutations and find no evidence to implicate mutations in PALLD as a cause of familial pancreatic cancer.
منابع مشابه
Palladin Mutation Causes Familial Pancreatic Cancer and Suggests a New Cancer Mechanism
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عنوان ژورنال:
- Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
دوره 18 4 شماره
صفحات -
تاریخ انتشار 2009